1.)     1971 –  Antitumor polysaccharides from some polyporaceae, Ganoderma appplanatum (PERS.) and Phellinus linteus (BERK. et CURT)

2.)     1999 –  The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis

3.)     2001 –  Antimutagenicity and induction of anticarcinogenic phase II enzymes by basidiomycetes

4.)     2001 –  Anti-tumor activity of the fruitbody extract of basidiomecetes, Phellinus linteus

5.)     2002 –  The roles of ERK 1/2 and p38 MAP kinases in the preventive mechanisms of mushroom Phellinus linteus against theinhibition of gap junctional intercellular communication by hydrogen peroxide

6.)     2002 –  Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides

7.)     2003 –  Acidic polysaccharides isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C

8.)     2003 –  Acidic polysaccharides isolated from Phellinus linteus induce phenotypic and functional maturation of murine dendritic cells

9.)     2003 –  Anti-angiogenic, antioxidant and xanthine oxidase inhibition activities of the mushroom Phellinus linteus

10.)   2003 –  Proteoglycan isolatd from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase

11.)   2003 –  Purification and characterization of acidic proteo-heteroglycan from the fruiting body of Phellinus linteus (Berk. & M.A.Curtis) Teng

12.)   2004 –  Acidic polysaccharide isolated from Phellinus linteus enhances through the up-regulation of nitric oxide and tumor necrosis factor-α from peritoneal macrophages

13.)   2004 –  Fractionation and anti-tumot activity of the mycelia of lliquid-cultured Phellinus linteus

14.)   2004 –  Proteoglycan isolatd from Phellinus linteus induces toll-like receptors 2-and 4-mediated maturation of murine dendritic cells via activation of ERK, p38 and NF-KB 

15.)   2004 –  Proteoglycan isolated from Phellinus linteus inhibits tumor growth through mechanisms leading to an activation of CD11c⁺CD8⁺ DC and type I helper T cell -dominant immue state

16.)   2005 –  Cambodian Phellinus linteus inhibits expertimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator

17.)   2005 –  Inhibition of IgE-dependent mouse triphasic cutaneous reaction by a boiling water fraction seperated  from mycelium of Phellinus linteus

18.)   2006 –  Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion

19.)   2008 –  Antiproliferative and antimetastatic effects of the ethanolic extract of Phellinus igniarius (Linnearus:Fries) Quelet

20.)   2009 –  Anti-cancer activities of Ginseng extract fermented with Phellinus linteus

21.)   2010 –  Medicinal mushroom Phellinus linteus as an alternative cancer therapy (Review)

22.)   2012 –  Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation

23.)   2013 –  Identification of an anticancer compound against HT-29 cells from Phellinus linteus grown on germinated brown rice

24.)   2015 – “Potent anticancer effects of bioactive mushroom extracts (Phellinus linteus) on a variety of human cencer cells

 
 

1.)    2003  –  Alleviation of experimental septic shock in mice by acidic polysaccharide isolated from the medicinal mushroom Phellnus linteus

2.)    2008  –  Pro- and antioxidative properties of medicinal mushroom extracts

 

1.)    2009  – Hispolon from Phellinus linteus has antiproliferative effects via MEM2-recruited ERK1/2 activitiy in breast and bladder cancer

 
 

1.)     2008 – Phellinus linteus suppress growth, angigogenesis and invasive behavior of breast cancer cells through the inhibition of AKT signalling

2.)     2009 – Hispolon from Phellinus linteus has antiproliferative effects via MEM2-recruited ERK1/2 activitiy in breast and bladder cancer

3.)     2012 – Biological activities of natural Phellinus SPP. mushroom in human cancer cells

 
 

1.)     2004 – Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells

2.)     2009 – Anti tumor effects and imminomidulating activities of Phellinus linteus extract in a CT-26 cell-injected colon cancer mouse model

3.)     2013 – Activation of P27kip 1-cyclin D1/E-CDK2 pathway by polysaccharide from Phellinus linteus leads to S-phase arrest in HT-29 cells

 

1.)     1997 – “근치 적 위 절제술을 시행받은 위암 환자에서 상황 (메시 마-엑스)의 항 종양 효과 (Antitumor effect of the situation (Messima-X) in gastric cancer patients undergoing curative gastrectomy)”

2.)     2008 – Hispolon induces apoptosis in huma gastric cancer cells through a ROS-mediated mitochondrial pathway

 

1.)     2019 – Involvement of Up-regulation of death receptors and Bim in hispolon-mediated TNF-related apoptosis-inducing ligand sensitization in human renal carninoma

 

1.)     2010 – Extracts of medicinal mushrooms Agaricus bisporus and Phellinus linteus induce proapoptotic effects in the human leukemia cell line K562

2.)     2013 – “Hispolon from Phellinus linteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukemia cells”

 
 

1.)     2003 – Extracts of Phellinus linteus grown on germinated brown rice suppress liver damage induced by carbon tetrachloride in rats

2.)     2003 – Inhibition of cytochrome P540 isozymes in rat liver microsomes by polysaccharides derived from Phellinus linteus

3.)     2004 – Mycelial culture of Phellinus linteus protects primary cultured rat hepatocytes against hepatoxins

4.)     2005 – Spontaneous regression of a large hepatocellular carcinoma with skull metastasis

5.)     2007 – Protective effects of Phellinus linteus extract against iron overload-medicated oxidative steress in cultured rate hepatocytes

6.)     2008 – Antagonizing TGF-β induced liver fibrosis by a retinoic acid derivative through regulation of ROS and calcium influx

7.)     2008 – Inhibition of transforming growth factor-β-induced liver fibrosis by a retinoic acid derivative via suppression of Col 1A2 promoter activity

8.)     2009 – Tumor-inhibitory and liver-protective effects of Phellinus igniarius extracellular polysaccharides

9.)     2011 – Orally administered mycelial culture of Phellinus linteus exhibits antitumor effects in hepatoma cell-bearing mice

10.)   2012 – “Protective effect of Phellinus linteus polysaccharide extracts against thioacetamide induced liver fibrosis in rats: a proteomics analysis “

11.)   2014 – Different immunology mechanisms of Phellinus igniarius in inhibiting growth of liver cancer melanoma cells

 
 
 

1.)     2006 – A case of spontaneous regression of hepatocellular carcinoma with multiple lung metastases

2.)     2006 – Mycelial extract of Phellinus linteus induces cell death in A549 lung cancer cells and elevation of nitric oxide in Raw 264.7 macrophage cells

3.)     2007 – Inhibitory effect of oral intake of natural Phellinus linteus fruit body on growth and pulmonary metastasis of B16/BL6 melanoma

4.)     2007 – Modulation of lung cancer growth arrest and apoptosis by Phellinus linteus

5.)     2008 – Phellifuropyranone A: A new furopyranone compound isolated from fruit bodies of wild Phellinus linteus

6.)     2011 – Inhibitory effect of oral administration of Sangwhang mushroom (Phellinus linteus) grown on germinated brown rice on experimental lung metastasis and tumor growth in mice

 
 

1.)     2006 – Partial characterization and immunostimulatory effect of a novel polysaccharide-protein complex extracted from Phellinus linteus

 
 

1.)     2004 – Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells

 
 
 

1.)     2006 – The apoptosis effect of hispolon from Phellinus linteus (Berkeley & Curtis) Teng on human epidermoid KB cells

 
 

1.)     2004 – Improvement insulin resistance and insulin secretion by water extracts of Cordyceps militaris, Phellinus linteus, and Paecilomyces tenuipes in 90% pancreatectomized rats

2.)     2013 – Anticancer effect of Phellinus linteus; potential clinical application in treating pancreactic ductal adenocarcinoma

 
 

1.)     2003 – Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus

2.)     2005 – Administration of extract of mushroom Phellinus linteus induces prostate enlargement with increase in stromal component in experimentally developed rat model of benign prostatic hyperplasia

3.)     2006 – Phellinus linteus sensitises apoptosis induced by doxorubicin in prostate cancer

4.)     2007 – Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells

5.)     2010 – Phellinus linteus extract sensitizes advanced prostate cancer cells to apoptosis in athymic nude mice

 
 

1.)     2005 – Spontaneous regression of a large hepatocellular carcinoma with skull metastasis